This course provides an in depth presentation of the sensorimotor, cognitive-linguistic, auditory, and cerebrovascular neurological networks that facilitate speech, language, cognition, and hearing in humans. Neurological models will be presented for differential diagnosis and localization of function, including neuropathologies and associated symptoms using top-down vs. bottom-up approach. The course will incorporate a strong translational component and clinical application to real problems affecting humans due to neurodevelopmental and/or acquired neurological breakdowns that affect the Central and Peripheral Nervous systems at different levels and associated systems.